San Francisco enters its matchup at Atlanta as one of the week's strongest bets. The 49ers are 2-0 straight up and against the spread on the road this season and have won and covered their last six regular-season road games. They also carry a 10-4-1 ATS run since late last season. The Falcons have failed to cover their last four home games and have hit the over in four straight, giving the 49ers and a slight lean to the over the edge.
Cleveland is another recommended play at Tennessee, though the Browns are favorites for the first time this season. They have won and covered four of five games but are just 1-6 in their last seven as favorites dating to late 2023. Cleveland has gone 6-2 to the under since late 2025, while the Titans are 0-11-1 ATS following straight-up wins since mid-2022, pointing to the Browns and a slight lean to the under.
In the Sunday night game at Allegiant Stadium, the Rams arrive on a 2-7 ATS skid since late 2025, while the Raiders are on a 6-1 ATS surge over the same span. Both teams have trended toward the over, with Las Vegas hitting in each of its last four games and Los Angeles on an 11-4 over run since mid-2025. The edge goes to the over and the Raiders.
Other notable trends include Minnesota, which is 5-0 straight up and 8-1-1 ATS since late 2025, favored at home against Indianapolis. Carolina holds a 14-8 ATS run since early last season against a Buccaneers team that is 1-14 ATS since mid-2025. In the AFC North, road teams are 9-2-1 ATS in the last 12 Bengals-Ravens meetings, favoring Cincinnati at Baltimore despite the Bengals failing to cover their last three games.
Sources: Las Vegas Review-Journal
Original reporting: Las Vegas Review-Journal →
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